Screening for factors such as mode of infection and parenthood during routine healthcare visits could help identify and provide resources to the most at-risk adolescents.Īdolescents and young people living with HIV (AYPLHIV) are central to our HIV prevention agenda. It is essential to identify and support AYPLHIV at a high risk of secondary transmission. Older age and early sexual debut were also strongly associated with a higher risk of secondary HIV transmission. Adolescents reporting none of these factors had a 4% probability of secondary transmission risk, rising to 89% probability with all five identified factors. Results:Ībout 14.2% of AYPLHIV reported high secondary HIV transmission risk. Multivariate logistic regressions tested baseline factors associated with secondary HIV transmission risk, controlling for covariates, with marginal effect modelling combinations. Questionnaires used validated scales where available and biomarkers were extracted from n = 67 health facilities. Design:Ī prospective cohort of AYLPHIV in South Africa recruited n = 1046 participants in 2014–2015, 93.6% of whom were followed up in 2016–2017 (1.5% mortality). We investigated predictors of secondary HIV transmission risk (past-year sexual risk combined with past-year viremia) among AYPLHIV in South Africa. Preventing secondary HIV transmission from adolescents and young people living with HIV (AYPLHIV) to their partners and children is critical to interrupting the HIV infection cycle in sub-Saharan Africa. This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Direct URL citations appear in the printed text and are provided in the HTML and PDF versions of this article on the journal's Website ( ). Supplemental digital content is available for this article. BDepartment of Sociology, University of Cape Town, Cape Town, South AfricaĬDepartment of Social Policy and Intervention, University of Oxford, Oxford, UKĭInstitute for Life Course Health Research, Department of Global Health, Stellenbosch UniversityĮUNICEF Eastern and Southern Africa Regional OfficeįDepartment of Psychiatry and Mental Health, University of Cape Town, Cape Town, South Africa.Ĭorrespondence to Elona Toska, DPhil, Centre for Social Science Research, University of Cape Town, Cape Town, South Africa 7700.
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